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Structure of 58483-95-7
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3-Amino-6-chloroisonicotinic acid is a bench-stable, electron-deficient heterocyclic scaffold featuring a para-chloro and ortho-amino substitution on the pyridine ring. This configuration enables direct integration into pharmaceutical intermediates and bioactive molecule synthesis, where its dual functional groups facilitate selective coupling reactions under standard conditions.
3-Amino-6-chloroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and cyclization protocols. Its ortho-amino and chloro substituents offer complementary reactivity for palladium-catalyzed cross-couplings and electrophilic substitutions, while the carboxylic acid facilitates amide formation and derivatization. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in scalable synthesis of pharmaceutical intermediates and functionalized pyridine scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: