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Structure of 108118-69-0
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2,6-Difluoropyridin-3-amine delivers a strategically positioned electron-deficient pyridine core with two fluorine substituents that enhance metabolic stability and modulate reactivity. This bench-stable amine integrates readily into pharmaceutical scaffolds, enabling efficient coupling reactions under mild conditions. The para-fluorinated arrangement supports directed functionalization and improves membrane permeability in bioactive molecules.
2,6-Difluoropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring via nucleophilic substitution due to the activating influence of the amine and the electron-withdrawing fluorine substituents. Its bench-stable nature, compatibility with standard coupling reactions, and utility in constructing heterocyclic scaffolds make it a practical choice for synthesizing kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: