3-Amino-5-bromo-2-chloropyridine

Name: 3-Amino-5-bromo-2-chloropyridine
Brand: ChemScene
Availability: InStock
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CAS No. 588729-99-1
Cat. No. CS-D0976
Purity≥97%
MDL No.MFCD02682092

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

3-Amino-5-bromo-2-chloropyridine|CS-D0976

Structure of 588729-99-1

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Description

3-Amino-5-bromo-2-chloropyridine features a tri-functional pyridine core enabling direct coupling in C–N and C–C bond formations. The amino group facilitates nucleophilic engagement, while bromo and chloro substituents support palladium-catalyzed cross-coupling. This electron-deficient scaffold delivers high reactivity under standard conditions.

Application

3-Amino-5-bromo-2-chloropyridine serves as a versatile building block in medicinal chemistry, enabling site-selective functionalization via cross-coupling and nucleophilic substitution reactions. The amino group facilitates derivatization, while the bromo and chloro substituents offer orthogonal reactivity for palladium-catalyzed coupling processes. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for multi-step synthesis of heterocyclic scaffolds and API intermediates.

General Information

CAS No. 588729-99-1
Cat. No. CS-D0976
Purity ≥97%
MDL No. MFCD02682092
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄BrClN₂
Molecular Weight 207.46
Synonym(s) None
SMILES NC1=CC(Br)=CN=C1Cl

Computational Chemistry Data

TPSA 38.91
LogP 2.0797
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Amino-5-bromo-2-chloropyridine

CAS No. 588729-99-1

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