Z-Glu-OtBu

Name: Z-Glu-OtBu
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 5891-45-2
Cat. No. CS-W008549
Purity≥97%
MDL No.MFCD00077016

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 5891-45-2

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Description

Z-Glu-OtBu features a protected glutamic acid side chain with a benzyl carbamate (Z) group at the α-amino terminus and tert-butyl ester functionality. This configuration enables stable incorporation into peptide sequences, facilitating efficient synthesis under standard conditions while offering orthogonal deprotection pathways for selective manipulation during complex assembly workflows.

Application

Z-Glu-OtBu serves as a robust amino acid building block for peptide synthesis, offering excellent bench stability and ease of purification. The benzyloxycarbonyl (Z) group provides reliable N-terminal protection, while the tert-butyl ester enables selective hydrolysis under mild acidic conditions. It functions effectively in standard coupling protocols, tolerates diverse reaction conditions, and facilitates efficient construction of complex peptide scaffolds.

General Information

CAS No. 5891-45-2
Cat. No. CS-W008549
Purity ≥97%
MDL No. MFCD00077016
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₇H₂₃NO₆
Molecular Weight None
Synonym(s) None
SMILES O=C(O)CC[C@H](NC(OCC1=CC=CC=C1)=O)C(OC(C)(C)C)=O

Computational Chemistry Data

TPSA 101.93
LogP 2.4879
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Glutamic acid and derivatives

Life Science Amino Acids and their Derivatives C-protected amino acid

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Z-Glu-OtBu

CAS No. 5891-45-2

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