Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2-methylbenzaldehyde

  • CAS No. 58966-34-0

  • Cat. No. CS-0061327
  • Molecule weight154.59
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-methylbenzaldehyde|CS-0061327

Structure of 58966-34-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 58966-34-0
  • Cat. No. CS-0061327
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇ClO
  • Molecular Weight 154.59
  • Synonym(s) 3-Chloro-6-methylbenzaldehyde
  • SMILES CC1=CC=C(C=C1C=O)Cl

Description

5-Chloro-2-methylbenzaldehyde features a chlorinated aromatic ring with ortho-methyl and aldehyde functionalities, enabling direct integration into Suzuki-Miyaura couplings and aldol condensations. This electron-deficient aldehyde offers enhanced reactivity in C–C bond formation under mild conditions, delivering high yields in pharmaceutical intermediates and functionalized heterocycles.

Application

5-Chloro-2-methylbenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic scaffolds. Its ortho-methyl and meta-chloro substituents provide directed functionalization opportunities and enhance metabolic stability in bioactive molecule design. The aldehyde group facilitates nucleophilic addition, condensation, and coupling reactions under mild conditions, offering reliable reactivity with broad functional group tolerance. Bench-stable and readily purified by distillation or recrystallization, it functions effectively in multistep synthesis, including the construction of heterocyclic intermediates and pharmaceutical candidates.

Synthesis

  • Route1
    • In-stock
      2-Bromo-4-chlorotoluene|CS-W002280
      27139-97-5
    • null|null
      68-12-2
    • ~68%
    • In-stock
      5-Chloro-2-methylbenzaldehyde|CS-0061327
      58966-34-0

    References

    • ACTELION PHARMACEUTICALS LTD Patent: WO2007/88514 A1, 2007 ; Location in patent: Page/Page column 37-38 ; WO 2007/088514 A1
  • Route2
    • In-stock
      4-Chloro-2-iodo-1-methylbenzene|CS-0134652
      33184-48-4
    • null|null
      68-12-2
    • ~94%
    • In-stock
      5-Chloro-2-methylbenzaldehyde|CS-0061327
      58966-34-0

    References

    • NERVIANO MEDICAL SCIENCES S.R.L.; BRASCA, Maria Gabriella; BINDI, Simona; CALDARELLI, Marina; NESI, Marcella; ORRENIUS, Sten Christian; PANZERI, Achille Patent: WO2014/19908 A2, 2014 ; Location in patent: Page/Page column 36 ;
  • Route3
    • null|null
      75-17-2
    • In-stock
      2-Chloro-4-methylaniline|CS-W018296
      615-65-6
    • ~35%
    • In-stock
      5-Chloro-2-methylbenzaldehyde|CS-0061327
      58966-34-0

    References

    • Chen, Li; Han, Xingchun; He, Yun; Yang, Song; Zhang, Zhuming Patent: US2009/163512 A1, 2009 ; Location in patent: Page/Page column 17 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.46092
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-2-methylbenzaldehyde sigma5-Chloro-2-methylbenzaldehyde manufacturer5-Chloro-2-methylbenzaldehyde price5-Chloro-2-methylbenzaldehyde structure5-Chloro-2-methylbenzaldehyde SDSbuy 5-Chloro-2-methylbenzaldehyde5-Chloro-2-methylbenzaldehyde supplier5-Chloro-2-methylbenzaldehyde uses5-Chloro-2-methylbenzaldehyde molecular weightprice of 5-Chloro-2-methylbenzaldehyde5-Chloro-2-methylbenzaldehyde chemical name formula of 5-Chloro-2-methylbenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label