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Boronic acid, (2-methyl-5-benzothiazolyl)-

  • CAS No. 590417-67-7

  • Cat. No. CS-0030599
  • Molecule weight193.03
  • Purity≥98%
  • MDL No.MFCD12025970

*For research and further manufacturing use only, not for direct human use.

Boronic acid, (2-methyl-5-benzothiazolyl)-|CS-0030599

Structure of 590417-67-7

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General Information

  • CAS No. 590417-67-7
  • Cat. No. CS-0030599
  • Purity ≥98%
  • MDL No. MFCD12025970
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BNO₂S
  • Molecular Weight 193.03
  • Synonym(s) 2-Methylbenzothiazole-5-boronic acid
  • SMILES CC1=NC2=CC(B(O)O)=CC=C2S1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering functionalized heteroaryl scaffolds with high efficiency. The ortho-methyl group enhances stability and modulates reactivity, while the thiazole ring provides a rigid, electron-deficient platform for downstream derivatization. Bench-stable under standard conditions, this reagent simplifies access to complex bioactive architectures in medicinal chemistry and materials science workflows.

Application

(2-Methylbenzo[d]thiazol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. Its stability under ambient conditions and compatibility with diverse functional groups facilitate straightforward purification and integration into complex molecular frameworks. The boronic acid moiety enables reliable C–C bond formation, making it particularly valuable for synthesizing heterocyclic scaffolds relevant to medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   0.28452
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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