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CS-W001157 4
Total: USD 88.00

8-Chloronaphthalen-1-amine

  • CAS No. 59107-51-6

  • Cat. No. CS-0095740
  • Purity≥98%
  • MDL No.MFCD00465087
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

8-Chloronaphthalen-1-amine|CS-0095740

Structure of 59107-51-6

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Description

8-Chloronaphthalen-1-amine is a chlorinated naphthalene derivative featuring a primary amine group at the 1-position. This electron-deficient aromatic scaffold enables direct incorporation into heterocyclic systems and conjugated frameworks. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench conditions, facilitating its use in synthetic transformations and materials development.

Application

8-Chloronaphthalen-1-amine serves as a versatile building block in the synthesis of pharmaceutical intermediates and functional materials. Its electron-deficient naphthalene core facilitates electrophilic substitution and palladium-catalyzed coupling reactions. The amine functionality enables straightforward derivatization via acylation, alkylation, or diazotization, while the chlorine substituent supports Suzuki-Miyaura and Buchwald-Hartwig couplings. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring orthogonal reactivity.

General Information

  • CAS No. 59107-51-6
  • Cat. No. CS-0095740
  • Purity ≥98%
  • MDL No. MFCD00465087
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈ClN
  • Molecular Weight 177.63
  • Synonym(s) 8-Chloro-phthalen-1-ylamine
  • SMILES NC1=C2C(Cl)=CC=CC2=CC=C1

Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.0754
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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