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Structure of 59107-51-6
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8-Chloronaphthalen-1-amine is a chlorinated naphthalene derivative featuring a primary amine group at the 1-position. This electron-deficient aromatic scaffold enables direct incorporation into heterocyclic systems and conjugated frameworks. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench conditions, facilitating its use in synthetic transformations and materials development.
8-Chloronaphthalen-1-amine serves as a versatile building block in the synthesis of pharmaceutical intermediates and functional materials. Its electron-deficient naphthalene core facilitates electrophilic substitution and palladium-catalyzed coupling reactions. The amine functionality enables straightforward derivatization via acylation, alkylation, or diazotization, while the chlorine substituent supports Suzuki-Miyaura and Buchwald-Hartwig couplings. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring orthogonal reactivity.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: