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Structure of 59340-27-1
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1,3,5-Trimethyl-1H-pyrazole-4-sulfonyl chloride features a sterically hindered pyrazole core with a reactive sulfonyl chloride group, enabling efficient coupling in synthetic transformations. The trimethyl substitution enhances solubility and stability under standard conditions, facilitating its use in building complex heterocyclic architectures.
1,3,5-Trimethyl-1H-pyrazole-4-sulfonyl chloride serves as a versatile sulfonyl chloride building block for constructing sulfonamide-containing scaffolds. Its pyrazole core offers enhanced stability and favorable solubility in organic media, while the trimethyl substitution pattern improves steric shielding and reduces undesired side reactivity. The reagent readily reacts with amines to form stable sulfonamides under mild conditions, enabling efficient functionalization in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: