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Structure of 59549-51-8
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5-Bromo-2-chloro-4-(methylthio)pyrimidine serves as a key heterocyclic building block for pharmaceutical intermediates and agrochemical synthesis. The molecule features orthogonal halogen handles—bromine at C5 and chlorine at C2—enabling selective cross-coupling reactions. The methylthio group at C4 enhances reactivity in transition-metal-catalyzed transformations while maintaining stability under standard handling conditions.
5-Bromo-2-chloro-4-(methylthio)pyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds through palladium-catalyzed cross-coupling reactions. The bromo and chloro substituents provide orthogonal reactivity for sequential functionalization, while the methylthio group offers a stable, easily displaced sulfur handle. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: