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Structure of 59669-59-9
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3-(tert-Butyl)isoxazol-5-amine features a sterically hindered tert-butyl group that enhances stability and solubility in organic media. This electron-rich isoxazole scaffold integrates readily into bioactive molecule frameworks, offering a robust handle for late-stage functionalization in medicinal chemistry and chemical biology applications.
3-(tert-Butyl)isoxazol-5-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its isoxazole core exhibits enhanced metabolic stability and favorable physicochemical properties. The amine functionality facilitates direct derivatization via acylation, alkylation, or coupling reactions, while the tert-butyl group provides steric protection and improved solubility. This compound demonstrates excellent bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis campaigns and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: