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CS-W001157 4
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1-Chloropropan-2-amine hydrochloride

  • CAS No. 5968-21-8

  • Cat. No. CS-0161780
  • Purity≥96%
  • MDL No.MFCD26407822

*For research and further manufacturing use only, not for direct human use.

1-Chloropropan-2-amine hydrochloride|CS-0161780

Structure of 5968-21-8

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General Information

  • CAS No. 5968-21-8
  • Cat. No. CS-0161780
  • Purity ≥96%
  • MDL No. MFCD26407822
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉Cl₂N
  • Molecular Weight 130.02
  • Synonym(s) 2-Propanamine, 1-chloro-, hydrochloride (9CI)
  • SMILES CC(N)CCl.[H]Cl

Description

1-Chloropropan-2-amine hydrochloride offers a reactive chloroalkyl handle for nucleophilic substitution, enabling efficient conjugation in peptide synthesis and bioconjugation workflows. This bench-stable salt features enhanced solubility in aqueous and polar organic media, facilitating use under standard conditions. The pendant amine group provides a site for further functionalization.

Application

1-Chloropropan-2-amine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient synthesis of β-amino alcohol motifs and nitrogen-containing heterocycles. Its bench-stable hydrochloride salt form facilitates handling and purification, while the chloro group supports nucleophilic substitution reactions for downstream functionalization. Widely used in peptide and small-molecule scaffold elaboration, it functions effectively in standard amine coupling and cyclization protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.9942
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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