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Structure of 59782-86-4
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2-Chloro-5-iodonicotinic acid is a halogenated pyridine carboxylic acid featuring strategically positioned chlorine and iodine substituents. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, serving as a key building block for bioactive heterocycles. The carboxylic acid group facilitates conjugation and derivatization under standard conditions.
2-Chloro-5-iodonicotinic acid serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its orthogonal halogenation pattern enables selective cross-coupling reactions, particularly Suzuki-Miyaura and Stille couplings, with high efficiency and excellent functional group tolerance. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: