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Structure of 59907-12-9
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1-Bromo-2-fluoro-3-methyl-benzene features a strategically positioned bromine, fluorine, and methyl group on a benzene ring, enabling selective cross-coupling reactions. The ortho-fluoro substituent enhances reactivity in palladium-catalyzed transformations, while the methyl group provides steric and electronic modulation. This compound serves as a key intermediate in the synthesis of functionalized aromatic systems for pharmaceutical and agrochemical applications.
1-Bromo-2-fluoro-3-methylbenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Negishi couplings. The ortho-fluoro and bromo substituents offer complementary reactivity for sequential functionalization, while the methyl group provides a stable, electron-donating handle. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of complex aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: