2,6-Dichloro-4-methyl-3-nitropyridine

Name: 2,6-Dichloro-4-methyl-3-nitropyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 60010-03-9
Cat. No. CS-W000772
Purity≥98%
MDL No.MFCD11110694

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,6-Dichloro-4-methyl-3-nitropyridine|CS-W000772

Structure of 60010-03-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 60010-03-9
Cat. No. CS-W000772
Purity ≥98%
MDL No. MFCD11110694
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄Cl₂N₂O₂
Molecular Weight 207.01
Synonym(s) 2,6-dichloro-4-methyl-3-nitro-pyridine
SMILES Cc1cc(Cl)nc(Cl)c1[N+]([O-])=O

Description

2,6-Dichloro-4-methyl-3-nitropyridine features a highly electron-deficient pyridine core flanked by two chlorine substituents and a methyl group, enabling selective coupling reactions. The nitro group at C3 enhances reactivity in nucleophilic substitution pathways. This scaffold offers robust stability under standard conditions and serves as a key intermediate in the synthesis of functionalized heterocycles for pharmaceutical and agrochemical applications.

Application

2,6-Dichloro-4-methyl-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling selective functionalization at the 3-position via reduction or substitution. The nitro group facilitates subsequent transformations into amino derivatives, while the dichloro substituents support palladium-catalyzed cross-coupling reactions. Its methyl group provides a handle for oxidation or further derivatization. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scalable medicinal chemistry campaigns and API intermediate development.

Synthesis

Route1
- 1253378-56-1
- ~%
- In-stock
  
  60010-03-9
References
- WO2010/122064 A1, ; Page/Page column 27 ; WO 2010/122064 A1
Route2
- In-stock
  
  23056-33-9
- ~%
- In-stock
  
  60010-03-9
References
- WO2011/26890 A1, ; WO 2011/026890 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 56.03
LogP 2.60502
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2,6-Dichloro-4-methyl-3-nitropyridine sigma2,6-Dichloro-4-methyl-3-nitropyridine manufacturer2,6-Dichloro-4-methyl-3-nitropyridine price2,6-Dichloro-4-methyl-3-nitropyridine structure2,6-Dichloro-4-methyl-3-nitropyridine SDSbuy 2,6-Dichloro-4-methyl-3-nitropyridine2,6-Dichloro-4-methyl-3-nitropyridine supplier2,6-Dichloro-4-methyl-3-nitropyridine uses2,6-Dichloro-4-methyl-3-nitropyridine molecular weightprice of 2,6-Dichloro-4-methyl-3-nitropyridine2,6-Dichloro-4-methyl-3-nitropyridine chemical name formula of 2,6-Dichloro-4-methyl-3-nitropyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,6-Dichloro-4-methyl-3-nitropyridine

CAS No. 60010-03-9

Recommended Products