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CS-W001157 4
Total: USD 88.00

Tiazofurin

  • CAS No. 60084-10-8

  • Cat. No. CS-0063433
  • Purity≥98%
  • MDL No.MFCD00866494

*For research and further manufacturing use only, not for direct human use.

Tiazofurin|CS-0063433

Structure of 60084-10-8

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General Information

  • CAS No. 60084-10-8
  • Cat. No. CS-0063433
  • Purity ≥98%
  • MDL No. MFCD00866494
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O₅S
  • Molecular Weight 260.27
  • Synonym(s) NSC 286193; Riboxamide
  • SMILES O=C(N)C1=CSC([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=N1

Description

Tiazofurin is a nucleoside analog featuring a thiophene ring fused to a furanose moiety, exhibiting potent inhibition of inosine monophosphate dehydrogenase (IMPDH). This mechanism disrupts purine biosynthesis, making it a valuable tool for studying metabolic pathways and antiviral activity. The compound demonstrates stability under standard bench conditions and facilitates targeted modulation of cellular nucleotide pools.

Synthesis

  • Route1

    References

    • Nucleosides, Nucleotides and Nucleic Acids, , vol. 23, # 4 p. 715 - 724
  • Route2
    • null|null
      52783-53-6
    • ~%
    • In-stock
      Tiazofurin|CS-0063433
      60084-10-8

    References

    • Nucleosides, Nucleotides and Nucleic Acids, , vol. 23, # 4 p. 715 - 724
  • Route3
    • null|null
      5517-61-3
    • ~%
    • In-stock
      Tiazofurin|CS-0063433
      60084-10-8

    References

    • Nucleosides, Nucleotides and Nucleic Acids, , vol. 23, # 4 p. 715 - 724

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   125.9
  • LogP   -1.604
  • H_Acceptors   7
  • H_Donors   4
  • Rotatable_Bonds   3

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