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Structure of 603122-52-7
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Methyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a bench-stable boronate ester featuring a para-fluorinated aryl moiety. This compound integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering efficient access to functionalized biaryl scaffolds under standard conditions. The tetramethyl-substituted dioxaborolane ring enhances stability and reactivity, enabling reliable coupling with diverse aryl halides.
Methyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The ortho-fluorine substituent enables directed metalation and facilitates subsequent functionalization, while the tetramethylboronate group offers excellent stability, ease of handling, and broad functional group tolerance. This reagent is particularly valuable in constructing substituted biaryl scaffolds and heterocyclic systems relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: