Benzyl 2-amino-2-methylpropanoate hydrochloride

Name: Benzyl 2-amino-2-methylpropanoate hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 60421-20-7
Cat. No. CS-0096008
Purity≥97%
MDL No.MFCD14155677

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Benzyl 2-amino-2-methylpropanoate hydrochloride|CS-0096008

Structure of 60421-20-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Benzyl 2-amino-2-methylpropanoate hydrochloride is a bench-stable, moisture-tolerant amino acid derivative featuring a sterically hindered α-carbon and a protected amine. This compound integrates readily into peptide synthesis workflows, serving as a key intermediate for constructing constrained peptidomimetics and bioactive scaffolds under standard conditions.

Application

Benzyl 2-amino-2-methylpropanoate hydrochloride serves as a versatile building block in peptide and heterocyclic synthesis, offering a stable, bench-ready source of the tert-leucine-derived amino group. Its tertiary α-amino functionality enables efficient coupling reactions with minimal racemization, while the benzyl ester facilitates straightforward deprotection under standard hydrogenolysis conditions. The hydrochloride salt enhances solubility and crystallinity, simplifying handling and purification in synthetic workflows.

General Information

CAS No. 60421-20-7
Cat. No. CS-0096008
Purity ≥97%
MDL No. MFCD14155677
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₆ClNO₂
Molecular Weight 229.70
Synonym(s) 2-amino-2-methyl-propionic acid benzyl ester hydrochloride
SMILES CC(C)(N)C(OCC1=CC=CC=C1)=O.[H]Cl

Computational Chemistry Data

TPSA 52.32
LogP 1.8889
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

60421-20-7 sigma60421-20-7 manufacturer60421-20-7 price60421-20-7 structure60421-20-7 SDSbuy 60421-20-760421-20-7 supplier60421-20-7 uses60421-20-7 molecular weightprice of 60421-20-760421-20-7 chemical name formula of 60421-20-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Benzyl 2-amino-2-methylpropanoate hydrochloride

CAS No. 60421-20-7

Recommended Products