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CS-W001157 4
Total: USD 88.00

Methyl 1-benzyl-4-hydroxypiperidine-4-carboxylate

  • CAS No. 60437-30-1

  • Cat. No. CS-0150907
  • Purity≥98%
  • MDL No.MFCD17453986

*For research and further manufacturing use only, not for direct human use.

Methyl 1-benzyl-4-hydroxypiperidine-4-carboxylate|CS-0150907

Structure of 60437-30-1

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General Information

  • CAS No. 60437-30-1
  • Cat. No. CS-0150907
  • Purity ≥98%
  • MDL No. MFCD17453986
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₉NO₃
  • Molecular Weight 249.31
  • Synonym(s) 4-Piperidinecarboxylic acid, 4-hydroxy-1-(phenylmethyl)-, methyl ester
  • SMILES COC(=O)C1(CCN(CC1)CC2=CC=CC=C2)O

Synthesis

  • Route1
    • null|null
      67-56-1
    • 1-Benzyl-4-hydroxypiperidine-4-carbonitrile|CS-0454240
      6094-60-6
    • ~89%
    • Methyl 1-benzyl-4-hydroxypiperidine-4-carboxylate|CS-0150907
      60437-30-1

    References

    • AiCuris GMBH and Co. KG Patent: US2010/22527 A1, 2010 ; Location in patent: Page/Page column 16 ; US 20100022527 A1
  • Route2
    • 1-Benzyl-4-hydroxypiperidine-4-carbonitrile|CS-0454240
      6094-60-6
    • ~%
    • Methyl 1-benzyl-4-hydroxypiperidine-4-carboxylate|CS-0150907
      60437-30-1

    References

    • Zheng, Guo Zhu; Brown, Brian S.; Turner, Sean C.; White, Tammie K.; Schmidt, Robert G.; Koenig, John R.; Lee, Chih-Hung Patent: US2005/80095 A1, 2005 ; Location in patent: Page/Page column 20 ;
  • Route3
    • null|null
      3612-20-2
    • ~%
    • Methyl 1-benzyl-4-hydroxypiperidine-4-carboxylate|CS-0150907
      60437-30-1

    References

    • Tsukamoto, Shin-ichi; Ichihara, Masato; Wanibuchi, Fumikazu; Usuda, Shinji; Hidaka, Kazuyuki; et al. Journal of Medicinal Chemistry, 1993 , vol. 36, # 16 p. 2292 - 2299

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.77
  • LogP   1.1865
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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