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Structure of 607-69-2
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2-Chloroquinazolin-4(3H)-one is a bench-stable heterocyclic scaffold featuring a chlorine substituent at the 2-position and a lactam carbonyl at the 4-position. This electron-deficient core integrates readily into medicinal chemistry campaigns, serving as a key building block for kinase inhibitors and bioactive molecules in drug discovery workflows.
2-Chloroquinazolin-4(3H)-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. Its stability under standard reaction conditions and compatibility with diverse nucleophiles facilitate rapid access to substituted quinazoline scaffolds prevalent in kinase inhibitor development. The compound functions effectively as a key intermediate in the synthesis of biologically active heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: