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Structure of 610-16-2
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2-(Dimethylamino)benzoic acid features a strongly electron-donating dimethylamino group positioned ortho to a carboxylic acid moiety, enabling robust intramolecular interactions. This structural arrangement enhances solubility in polar solvents and facilitates efficient coupling reactions in peptide synthesis and pharmaceutical intermediates. The molecule exhibits excellent stability under standard bench conditions.
2-(Dimethylamino)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dimethylaminobenzoic scaffold exhibits favorable reactivity in amide coupling, esterification, and cyclization reactions, with good bench stability and ease of purification. The electron-donating dimethylamino group enhances nucleophilicity at the aromatic ring, facilitating downstream functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: