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CS-W001157 4
Total: USD 88.00

8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine

  • CAS No. 611240-68-7

  • Cat. No. CS-0465980
  • Molecule weight221.57
  • Purity≥98%
  • MDL No.MFCD11559012

*For research and further manufacturing use only, not for direct human use.

8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine|CS-0465980

Structure of 611240-68-7

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General Information

  • CAS No. 611240-68-7
  • Cat. No. CS-0465980
  • Purity ≥98%
  • MDL No. MFCD11559012
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃ClF₃N₃
  • Molecular Weight 221.57
  • Synonym(s) 8-chloranyl-2-(trifluoromethyl)imidazo[1,2-a]pyrazine
  • SMILES C1=CN2C=C(C(F)(F)F)N=C2C(=N1)Cl

Synthesis

  • Route1
    • 2-(Trifluoromethyl)imidazo[1,2-a]pyrazin-8(7H)-one|CS-1196090
      850445-47-5
    • ~98%
    • In-stock
      8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine|CS-0465980
      611240-68-7

    References

    • Janssen Pharmaceutica NV Patent: US2012/329792 A1, 2012 ; Location in patent: Page/Page column 34 ;
  • Route2
    • In-stock
      3-Chloro-2-pyrazinamine|CS-W007499
      6863-73-6
    • null|null
      431-35-6
    • ~%
    • In-stock
      8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine|CS-0465980
      611240-68-7
    • 8-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyrazine|CS-0500587
      850406-42-7

    References

    • CARDIOME PHARMA CORPORATION Patent: WO2005/34837 A2, 2005 ; Location in patent: Page/Page column 43 ; WO 2005/034837 A2
  • Route3
    • null|null
      777851-75-9
    • ~%
    • In-stock
      8-Chloro-2-(trifluoromethyl)imidazo[1,2-a]pyrazine|CS-0465980
      611240-68-7

    References

    • MERCK and CO., INC. Patent: WO2003/82817 A2, 2003 ; Location in patent: Page/Page column 54 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.4015
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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