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Structure of 613-30-9
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2-Methyl-6-nitroquinoline features a fused bicyclic core with complementary electron-deficient and sterically accessible functional groups. This configuration enables direct incorporation into heterocyclic scaffolds, serving as a key intermediate in the synthesis of bioactive quinoline derivatives and fluorescent probes. The para-nitro substitution enhances reactivity in nucleophilic aromatic substitution processes.
2-Methyl-6-nitroquinoline serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its electron-deficient quinoline core, combined with ortho-directed nitro and methyl substituents, enables regioselective functionalization via palladium-catalyzed cross-coupling, nucleophilic substitution, and reduction protocols. The compound exhibits bench stability and facilitates the synthesis of advanced pharmaceutical intermediates and fluorescent scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: