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Structure of 65079-19-8
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2-Methylquinolin-6-amine features a fused heterocyclic core with a strategically positioned amine and methyl group, enabling direct incorporation into pharmaceutical scaffolds. The electron-rich quinoline framework supports efficient metal-catalyzed coupling reactions, while the ortho-methyl substitution enhances metabolic stability. This compound serves as a key intermediate in the synthesis of kinase inhibitors and fluorescent probes.
2-Methylquinolin-6-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through palladium-catalyzed cross-coupling reactions. Its ortho-directing amine group facilitates regioselective functionalization, while the methyl substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it well-suited for both lead optimization and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: