5-Bromo-2-chloro-1,3-benzoxazole

Name: 5-Bromo-2-chloro-1,3-benzoxazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1030377-54-8
Cat. No. CS-W003776
Purity≥96%
MDL No.MFCD11111724

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-chloro-1,3-benzoxazole|CS-W003776

Structure of 1030377-54-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Bromo-2-chloro-1,3-benzoxazole integrates a bromine atom at the 5-position and a chlorine substituent at the 2-position within a stable benzoxazole core. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling direct coupling reactions via palladium-catalyzed cross-coupling protocols. The orthogonal reactivity of the halogens facilitates sequential functionalization, streamlining access to complex aromatic scaffolds.

Application

5-Bromo-2-chloro-1,3-benzoxazole serves as a versatile heterocyclic building block for late-stage functionalization in medicinal chemistry and materials science. The ortho-halogenated scaffold enables palladium-catalyzed cross-coupling reactions with high regioselectivity, while the benzoxazole core offers enhanced metabolic stability and favorable pharmacophore properties. Bench-stable and readily purified by recrystallization, it facilitates efficient synthesis of complex aromatic systems and API intermediates.

General Information

CAS No. 1030377-54-8
Cat. No. CS-W003776
Purity ≥96%
MDL No. MFCD11111724
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₃BrClNO
Molecular Weight 232.46
Synonym(s) 5-Bromo-2-chlorobenzo[d]oxazole
SMILES BrC1=CC(N=C2Cl)=C(O2)C=C1

Computational Chemistry Data

TPSA 26.03
LogP 3.2437
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Benzooxazole compounds

Key Words

5-Bromo-2-chloro-1,3-benzoxazole sigma5-Bromo-2-chloro-1,3-benzoxazole manufacturer5-Bromo-2-chloro-1,3-benzoxazole price5-Bromo-2-chloro-1,3-benzoxazole structure5-Bromo-2-chloro-1,3-benzoxazole SDSbuy 5-Bromo-2-chloro-1,3-benzoxazole5-Bromo-2-chloro-1,3-benzoxazole supplier5-Bromo-2-chloro-1,3-benzoxazole uses5-Bromo-2-chloro-1,3-benzoxazole molecular weightprice of 5-Bromo-2-chloro-1,3-benzoxazole5-Bromo-2-chloro-1,3-benzoxazole chemical name formula of 5-Bromo-2-chloro-1,3-benzoxazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-2-chloro-1,3-benzoxazole

CAS No. 1030377-54-8

Recommended Products