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Structure of 6178-52-5
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4-Benzenesulfonyl-butyric acid features a sulfonated aromatic ring linked to a carboxylic acid-bearing aliphatic chain, combining strong electron-withdrawing character with enhanced solubility. This structural motif enables robust participation in synthetic transformations requiring polar, stable functional groups.
4-Benzenesulfonyl-butyric acid serves as a versatile synthetic intermediate for constructing sulfonamide-containing heterocycles and bioactive scaffolds. Its benzenesulfonyl group provides strong electron-withdrawing character and enhanced stability, while the carboxylic acid functionality enables direct coupling reactions or derivatization via standard esterification, amidation, or decarboxylation protocols. The molecule exhibits good bench stability and facilitates purification through crystallization or chromatography, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: