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Structure of 5382-49-0
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1,2,3,4-Tetrahydroquinoline-6-carboxylic acid features a fully saturated quinoline core with a carboxylic acid group at the C6 position, enabling direct conjugation or derivatization. This scaffold combines enhanced solubility and metabolic stability with a rigid, electron-rich aromatic system, making it valuable for medicinal chemistry applications. The pendant carboxylic acid serves as a versatile handle for peptide coupling, esterification, or amide formation under standard conditions.
1,2,3,4-Tetrahydroquinoline-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and natural product synthesis. Its carboxylic acid functionality enables direct derivatization via amide, ester, or acyl chloride formation, while the saturated quinoline core offers enhanced metabolic stability and tunable lipophilicity. The molecule exhibits good bench stability and compatibility with standard coupling protocols, facilitating integration into multi-step synthetic sequences targeting bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: