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CS-W001157 4
Total: USD 88.00

(4-Methoxyphenyl)(4-(trifluoromethyl)phenyl)methanone

  • CAS No. 6185-76-8

  • Cat. No. CS-0695609
  • Purity≥97%
  • MDL No.MFCD13152565

*For research and further manufacturing use only, not for direct human use.

(4-Methoxyphenyl)(4-(trifluoromethyl)phenyl)methanone|CS-0695609

Structure of 6185-76-8

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General Information

  • CAS No. 6185-76-8
  • Cat. No. CS-0695609
  • Purity ≥97%
  • MDL No. MFCD13152565
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₁F₃O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES COC1=CC=C(C=C1)C(=O)C1=CC=C(C=C1)C(F)(F)F

Description

This ketone features a methoxy-substituted aryl ring paired with a trifluoromethyl-bearing phenyl group, delivering enhanced electron-withdrawing character and improved solubility in organic solvents. The structural combination enables efficient integration into pharmaceutical intermediates and advanced materials.

Application

(4-Methoxyphenyl)(4-(trifluoromethyl)phenyl)methanone serves as a versatile aryl ketone building block for pharmaceutical and agrochemical synthesis. Its dual functionalization—electron-donating methoxy and strongly electron-withdrawing trifluoromethyl groups—enables predictable reactivity in nucleophilic additions, cross-coupling reactions, and heterocycle formation. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in standard synthetic workflows requiring polar, aromatic ketones with tailored electronic properties.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.945
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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