Tribenzylamine

Name: Tribenzylamine
Brand: ChemScene
Availability: InStock
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CAS No. 620-40-6
Cat. No. CS-0071604
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

2-(2,6-dioxopiperidin-3-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-1,3-dione is a thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.

Application

Tribenzylamine serves as a versatile, bench-stable tertiary amine in synthetic organic chemistry, enabling efficient catalysis in C–H functionalization and cross-coupling reactions. Its triaryl substitution provides excellent solubility and thermal stability, facilitating purification and scalability. Widely used as a ligand or additive in transition metal-catalyzed transformations, it functions effectively in palladium- and copper-mediated processes, offering robust performance across diverse reaction conditions.

General Information

CAS No. 620-40-6
Cat. No. CS-0071604
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₁N
Molecular Weight 287.40
Synonym(s) N,N-dibenzyl-1-phenylmethanamine; Tribenzylamine
SMILES N(CC1=CC=CC=C1)(CC2=CC=CC=C2)CC3=CC=CC=C3

Computational Chemistry Data

TPSA 3.24
LogP 4.889
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Tribenzylamine

CAS No. 620-40-6

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