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Structure of 62019-56-1
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2,4-Dichlorothiazole-5-carboxylic acid features a rigid thiazole core functionalized with two chlorine atoms and a carboxylic acid group, enabling direct incorporation into bioactive scaffolds. The electron-deficient heterocycle facilitates cross-coupling reactions under mild conditions, while the carboxylic acid provides a handle for derivatization via amide or ester formation. This compound serves as a key building block in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.
2,4-Dichlorothiazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. The dichloro substitution pattern provides orthogonal reactivity for sequential functionalization, while the carboxylic acid group facilitates direct derivatization or salt formation. Its bench-stable crystalline form supports reliable handling and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: