Benzyl carbamate

Name: Benzyl carbamate
Brand: ChemScene
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CAS No. 621-84-1
Cat. No. CS-W004984
Purity≥96%
MDL No.MFCD00007965

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 621-84-1

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Description

Benzyl carbamate serves as a stable, bench-friendly protecting group for primary amines in synthetic organic chemistry. This robust moiety enables selective N-alkylation and subsequent mild deprotection under hydrogenolysis conditions, facilitating efficient peptide coupling and amine functionalization workflows without interference from side reactions.

Application

Benzyl carbamate serves as a stable, bench-friendly protecting group for primary amines, enabling straightforward deprotection under mild hydrogenolysis conditions. It exhibits excellent functional group tolerance and is widely employed in peptide synthesis and medicinal chemistry workflows to prevent amine side reactions. Its compatibility with diverse reaction conditions facilitates efficient multi-step syntheses.

General Information

CAS No. 621-84-1
Cat. No. CS-W004984
Purity ≥96%
MDL No. MFCD00007965
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉NO₂
Molecular Weight 151.16
Synonym(s) Carbamic Acid Benzyl Ester
SMILES NC(OCC1=CC=CC=C1)=O

Computational Chemistry Data

TPSA 52.32
LogP 1.2819
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H412
Precautionary Statements : P273-P501

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Benzyl carbamate

CAS No. 621-84-1

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