Phenyl carbamate

Name: Phenyl carbamate
Brand: ChemScene
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CAS No. 622-46-8
Cat. No. CS-0095625
Purity≥95%
MDL No.MFCD00007961

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 622-46-8

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Description

Phenyl carbamate features a stable aryl-carbamate linkage ideal for protecting amine functionalities during synthetic sequences. This bench-stable derivative integrates readily into multi-step syntheses, offering reliable deprotection under mild conditions. Its electron-rich aromatic ring enhances compatibility with diverse reaction environments.

Application

Phenyl carbamate serves as a stable, bench-ready protecting group for primary amines, enabling selective N-protective strategies in peptide synthesis and medicinal chemistry. It facilitates mild deprotection under physiological or basic conditions, offering excellent functional group tolerance and compatibility with diverse reaction environments. Its predictable cleavage profile and ease of purification make it a practical choice for multi-step synthetic sequences.

General Information

CAS No. 622-46-8
Cat. No. CS-0095625
Purity ≥95%
MDL No. MFCD00007961
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇NO₂
Molecular Weight 137.14
Synonym(s) Carbamic acid, phenyl ester
SMILES NC(OC1=CC=CC=C1)=O

Computational Chemistry Data

TPSA 52.32
LogP 1.1441
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352-P304+P340

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Phenyl carbamate

CAS No. 622-46-8

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