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CS-W001157 4
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Methyl 4-bromothiophene-2-carboxylate

  • CAS No. 62224-16-2

  • Cat. No. CS-W022849
  • Purity≥96%
  • MDL No.MFCD06203668

*For research and further manufacturing use only, not for direct human use.

Methyl 4-bromothiophene-2-carboxylate|CS-W022849

Structure of 62224-16-2

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General Information

  • CAS No. 62224-16-2
  • Cat. No. CS-W022849
  • Purity ≥96%
  • MDL No. MFCD06203668
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrO₂S
  • Molecular Weight 221.07
  • Synonym(s) None
  • SMILES COC(=O)C1=CC(Br)=CS1

Description

Methyl 4-bromothiophene-2-carboxylate features a brominated thiophene core with a methyl ester group, offering a reactive handle for cross-coupling and functionalization. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring electron-deficient heterocyclic scaffolds.

Application

Methyl 4-bromothiophene-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromo functionality. The methyl ester group offers synthetic flexibility for subsequent transformations, while the thiophene core provides stability and compatibility with standard reaction conditions. Its bench-stable nature and predictable reactivity make it suitable for iterative synthesis workflows in medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.2972
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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