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CS-W001157 4
Total: USD 88.00

4-[2-(Dimethylamino)ethoxy]aniline

  • CAS No. 62345-76-0

  • Cat. No. CS-0208355
  • Molecule weight180.25
  • Purity≥95%
  • MDL No.MFCD07801177

*For research and further manufacturing use only, not for direct human use.

4-[2-(Dimethylamino)ethoxy]aniline|CS-0208355

Structure of 62345-76-0

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General Information

  • CAS No. 62345-76-0
  • Cat. No. CS-0208355
  • Purity ≥95%
  • MDL No. MFCD07801177
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆N₂O
  • Molecular Weight 180.25
  • Synonym(s) N-[2-(4-aminophenoxy)ethyl]-N,N-dimethylamine
  • SMILES CN(C)CCOC1=CC=C(C=C1)N

Synthesis

  • Route1
    • N,N-dimethyl-2-(4-nitrophenoxy)ethan-1-amine|CS-0453160
      51344-13-9
    • ~10%
    • 4-[2-(Dimethylamino)ethoxy]aniline|CS-0208355
      62345-76-0

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2008/77885 A2, 2008 ; Location in patent: Page/Page column 22 ; WO 2008/077885 A2
  • Route2
    • 4-(2-Chloroethoxy)aniline|CS-0661610
      27692-35-9
    • null|null
      124-40-3
    • ~%
    • 4-[2-(Dimethylamino)ethoxy]aniline|CS-0208355
      62345-76-0

    References

    • WO2005/68452 A1, ; Page/Page column 42 ; WO 2005/068452 A1
  • Route3
    • null|null
      866021-31-0
    • ~79%
    • 4-[2-(Dimethylamino)ethoxy]aniline|CS-0208355
      62345-76-0

    References

    • Clegg, Nicola J.; Paruthiyil, Sreenivasan; Leitman, Dale C.; Scanlan, Thomas S. Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5989 - 6003

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302+H312+H332-H314
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P362+P364-P363-P405-P501

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   1.2092
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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