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7-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carbaldehyde

  • CAS No. 623564-20-5

  • Cat. No. CS-0454295
  • Molecule weight165.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carbaldehyde|CS-0454295

Structure of 623564-20-5

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General Information

  • CAS No. 623564-20-5
  • Cat. No. CS-0454295
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁N₃O
  • Molecular Weight 165.19
  • Synonym(s) Imidazo[1,2-a]pyrazine-2-carboxaldehyde, 5,6,7,8-tetrahydro-7-methyl- (9CI)
  • SMILES CN1CCN2C=C(C=O)N=C2C1

Synthesis

  • Route1
    • Ethyl 7-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylate|CS-0734686
      623564-19-2
    • ~41%
    • 7-Methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carbaldehyde|CS-0454295
      623564-20-5

    References

    • WYETH Patent: WO2003/93277 A1, 2003 ; Location in patent: Page/Page column 70 ;
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 15 p. 4623 - 4637

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   38.13
  • LogP   0.141
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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