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CS-W001157 4
Total: USD 88.00

2-(Benzyloxy)phenol

  • CAS No. 6272-38-4

  • Cat. No. CS-0156162
  • Purity≥96%
  • MDL No.MFCD00002186

*For research and further manufacturing use only, not for direct human use.

2-(Benzyloxy)phenol|CS-0156162

Structure of 6272-38-4

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General Information

  • CAS No. 6272-38-4
  • Cat. No. CS-0156162
  • Purity ≥96%
  • MDL No. MFCD00002186
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂O₂
  • Molecular Weight None
  • Synonym(s) Catechol Monobenzyl Ether
  • SMILES C1=CC=C(C=C1)COC2=CC=CC=C2O

Description

2-(Benzyloxy)phenol was used in the synthesis of 2-(benzyloxy)hydroquinone.

Application

2-(Benzyloxy)phenol serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of complex phenolic architectures. Its benzyloxy group offers stable protection for phenolic hydroxyls under mild conditions, readily removable via acid-catalyzed cleavage. The molecule exhibits excellent functional group tolerance and bench stability, facilitating its use in multistep synthesis, heterocycle formation, and the preparation of advanced intermediates for medicinal chemistry applications.

Synthesis

  • Route1
    • null|null
      100-44-7
    • null|null
      120-80-9
    • ~54%
    • In-stock
      2-(Benzyloxy)phenol|CS-0156162
      6272-38-4

    References

    • Maekelae, Taru; Matikainen, Jorma; Waehaelae, Kristiina; Hase, Tapio Tetrahedron, 2000 , vol. 56, # 13 p. 1873 - 1882
  • Route2
    • null|null
      100-39-0
    • null|null
      120-80-9
    • ~88%
    • In-stock
      2-(Benzyloxy)phenol|CS-0156162
      6272-38-4

    References

    • Li, Yue; Chen, Shu-Han; Ou, Tian-Miao; Tan, Jia-Heng; Li, Ding; Gu, Lian-Quan; Huang, Zhi-Shu Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 6 p. 2074 - 2083
  • Route3
    • null|null
      93758-13-5
    • ~99%
    • In-stock
      2-(Benzyloxy)phenol|CS-0156162
      6272-38-4

    References

    • Ramesh; Ravindranath; Das, Biswanath Journal of Organic Chemistry, 2003 , vol. 68, # 18 p. 7101 - 7103

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.9712
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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