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Structure of 628-20-6
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4-Chlorobutyronitrile is a versatile synthetic intermediate featuring a chlorine atom at the γ-position relative to a nitrile group. This arrangement enables selective functionalization in pharmaceutical and agrochemical synthesis, offering enhanced reactivity for nucleophilic substitution or elimination pathways under standard conditions. The molecule combines high stability with predictable transformation behavior.
4-Chlorobutyronitrile serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and bioactive intermediates. Its terminal nitrile and β-chloroalkyl functionalities offer orthogonal reactivity for nucleophilic substitution, cyclization, and transition-metal-catalyzed coupling processes. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis workflows in medicinal chemistry and process development.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3276
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H227-H301-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: