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CS-W001157 4
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5-Chloropentanenitrile

  • CAS No. 6280-87-1

  • Cat. No. CS-W022361
  • Purity≥98%
  • MDL No.MFCD00001977
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chloropentanenitrile|CS-W022361

Structure of 6280-87-1

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Description

5-Chloropentanenitrile features a terminal nitrile group flanked by a chlorine-substituted alkyl chain, enabling direct integration into synthetic sequences requiring electrophilic or nucleophilic functionalization. This bifunctional scaffold supports efficient derivatization in medicinal chemistry and materials synthesis under standard conditions.

Application

5-Chloropentanenitrile serves as a versatile bifunctional building block for synthetic organic chemistry, enabling efficient access to heterocyclic scaffolds and functionalized aliphatic chains. Its nitrile group facilitates nucleophilic addition and hydrolysis to carboxylic acids, while the terminal chloroalkyl moiety supports SN2 transformations with amines, thiols, and nucleophilic heterocycles. The compound exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for use in medicinal chemistry lead optimization and process-scale synthesis.

General Information

  • CAS No. 6280-87-1
  • Cat. No. CS-W022361
  • Purity ≥98%
  • MDL No. MFCD00001977
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈ClN
  • Molecular Weight 117.58
  • Synonym(s) Chlorovaleronitrile
  • SMILES N#CCCCCCl

Computational Chemistry Data

  • TPSA   23.79
  • LogP   1.91908
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3276
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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