5,6-Dimethylpyrazin-2-amine

Name: 5,6-Dimethylpyrazin-2-amine
Brand: ChemScene
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CAS No. 6294-70-8
Cat. No. CS-W020409
Purity≥98%
MDL No.MFCD09835026

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 6294-70-8

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Description

5,6-Dimethylpyrazin-2-amine features a pyrazine core with methyl groups at the 5 and 6 positions, enhancing electron density and steric profile. This bench-stable heterocycle integrates readily into ligand design, offering robust coordination in transition metal complexes. The primary amine facilitates conjugation and functionalization under standard conditions.

Application

5,6-Dimethylpyrazin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyrazine core exhibits favorable stability and moderate basicity, facilitating downstream derivatization while maintaining compatibility with common protecting group strategies. The molecule functions effectively in transition-metal-catalyzed cross-coupling processes and provides a rigid, electron-deficient scaffold for structure-activity studies.

General Information

CAS No. 6294-70-8
Cat. No. CS-W020409
Purity ≥98%
MDL No. MFCD09835026
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₉N₃
Molecular Weight None
Synonym(s) 6-Amino-2,3-dimethylpyrazine
SMILES NC1=NC(C)=C(N=C1)C

Computational Chemistry Data

TPSA 51.8
LogP 0.67564
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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5,6-Dimethylpyrazin-2-amine

CAS No. 6294-70-8

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