(4-Chloropyridin-2-yl)methanol

Name: (4-Chloropyridin-2-yl)methanol
Brand: ChemScene
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CAS No. 63071-10-3
Cat. No. CS-W003408
Purity≥95%
MDL No.MFCD07437885

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(4-Chloropyridin-2-yl)methanol|CS-W003408

Structure of 63071-10-3

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Description

(4-Chloropyridin-2-yl)methanol features a pyridine ring bearing a chlorine atom at the 4-position and a methanol group at the 2-position. This configuration imparts enhanced reactivity for nucleophilic substitution and facilitates incorporation into pharmaceutical intermediates. The compound exhibits bench-stable handling characteristics and demonstrates good solubility in common organic solvents, enabling seamless integration into multistep synthetic sequences.

Application

(4-Chloropyridin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient functionalization via nucleophilic substitution at the chloro position. Its pyridyl methanol motif offers enhanced solubility and handles well under standard reaction conditions. The molecule functions as a key intermediate in constructing heterocyclic scaffolds and supports diverse transformations, including coupling reactions and derivatization of nitrogen-containing rings, with predictable reactivity and straightforward purification.

General Information

CAS No. 63071-10-3
Cat. No. CS-W003408
Purity ≥95%
MDL No. MFCD07437885
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆ClNO
Molecular Weight 143.57
Synonym(s) 4-Chloro-2-(hydroxymethyl)pyridine
SMILES OCC1=NC=CC(Cl)=C1

Computational Chemistry Data

TPSA 33.12
LogP 1.2273
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(4-Chloropyridin-2-yl)methanol

CAS No. 63071-10-3

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