4-Chloro-2-pyridinecarbaldehyde

Name: 4-Chloro-2-pyridinecarbaldehyde
Brand: ChemScene
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CAS No. 63071-13-6
Cat. No. CS-D1623
Purity≥97%
MDL No.MFCD07437896

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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4-Chloro-2-pyridinecarbaldehyde|CS-D1623

Structure of 63071-13-6

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Description

4-Chloro-2-pyridinecarbaldehyde features a chlorine-substituted pyridine ring fused with an aldehyde group, enabling direct incorporation into heterocyclic scaffolds. This electron-deficient heteroaryl aldehyde serves as a key building block in medicinal chemistry and catalyst design, offering enhanced reactivity in nucleophilic addition and condensation reactions under standard conditions.

Application

4-Chloro-2-pyridinecarbaldehyde serves as a versatile building block in medicinal chemistry and catalysis, enabling efficient construction of pyridine-based heterocycles. Its electrophilic aldehyde group facilitates nucleophilic addition reactions, while the chloropyridine moiety supports palladium-catalyzed cross-coupling transformations. The compound exhibits excellent bench stability and compatibility with common protecting groups, facilitating straightforward purification and integration into multi-step syntheses.

General Information

CAS No. 63071-13-6
Cat. No. CS-D1623
Purity ≥97%
MDL No. MFCD07437896
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄ClNO
Molecular Weight None
Synonym(s) 4-Chloro-2-pyridinecarboxaldehyde; 4-Chloro-2-formylpyridine; 4-Chloropicolinaldehyde; 4-Chloropyridine-2-carboxaldehyde; 2-pyridinecarboxaldehyde, 4-chloro-
SMILES O=CC1=NC=CC(Cl)=C1

Computational Chemistry Data

TPSA 29.96
LogP 1.5475
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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4-Chloro-2-pyridinecarbaldehyde

CAS No. 63071-13-6

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