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Structure of 63071-71-6
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1H-Indole-2-carbothioamide features a fused indole core with a thiocarbonyl-amide functional group at the 2-position, enabling robust coordination in metal-ligand systems. This scaffold integrates readily into bioactive molecule design due to its planar geometry and hydrogen-bonding capacity, offering enhanced solubility and stability under standard bench conditions.
1H-Indole-2-carbothioamide serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via cyclization and coupling reactions. Its thiocarbonyl group exhibits predictable reactivity in nucleophilic additions and condensation processes, while the indole core provides structural rigidity and π-systems beneficial for target engagement. The compound demonstrates bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: