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Structure of 6309-16-6
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1-(Thiophen-2-yl)ethanamine features a thiophene ring directly linked to an ethylamine side chain, delivering a robust heteroaromatic scaffold with enhanced solubility and stability. This moiety integrates readily into bioactive molecules, particularly in medicinal chemistry applications where electron-rich aromatic systems improve target affinity. The amine group enables straightforward derivatization under standard conditions.
1-(Thiophen-2-yl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard amine functionalization. Its thiophene moiety provides enhanced metabolic stability and π-stacking potential, while the primary amine facilitates straightforward conjugation, reductive amination, and peptide coupling. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthetic workflows in API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: