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Structure of 6311-37-1
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4-Amino-3-bromobenzoic acid features a bromine atom at the meta position relative to the carboxylic acid, paired with an amino group ortho to the carboxylate. This electron-rich aromatic scaffold enables direct coupling in peptide synthesis and serves as a key building block for bioactive heterocycles. The molecule exhibits enhanced solubility in polar solvents and stability under standard bench conditions.
4-Amino-3-bromobenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-bromo and amino groups enable sequential functionalization via Pd-catalyzed cross-coupling and electrophilic substitution, while the carboxylic acid facilitates derivatization and salt formation. The compound exhibits good bench stability and is readily purified by recrystallization, supporting scalable access to complex scaffolds in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: