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Structure of 63176-44-3
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2-Methyl-1H-indole-3-carboxylic acid features a sterically accessible indole core with a carboxylic acid group at the 3-position, enabling direct conjugation in bioconjugation and medicinal chemistry applications. This bench-stable scaffold integrates readily into peptide architectures and small-molecule libraries, offering enhanced solubility and metabolic stability compared to unsubstituted analogs.
2-Methyl-1H-indole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of indole-based scaffolds prevalent in bioactive molecules. Its carboxylic acid functionality facilitates direct coupling reactions, while the methyl group at the 2-position enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard peptide coupling protocols, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: