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Structure of 633327-50-1
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5-Fluoro-2-methyl-4-nitroaniline features a trifunctional aromatic core with electron-withdrawing nitro and fluoro groups paired with an activating methyl substituent. This combination enables selective coupling reactions under mild conditions, making it valuable for synthesizing fluorinated heterocycles and pharmaceutical intermediates.
5-Fluoro-2-methyl-4-nitroaniline serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its nitro group facilitates subsequent reduction to the amine for Ullmann or Suzuki coupling, while the fluorine and methyl substituents offer orthogonal reactivity and metabolic stability. The compound exhibits excellent bench stability and ease of purification, making it well-suited for multi-step synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: