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Structure of 63349-52-0
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Methyl 2-(4-iodophenyl)acetate is a bench-stable aryl iodide derivative featuring a pendant ester group, enabling direct coupling in Pd-catalyzed cross-coupling reactions. The para-iodo substitution provides high reactivity in Suzuki, Stille, and Negishi transformations, while the methyl ester offers straightforward derivatization pathways. This compound serves as a key building block for functionalized biaryl architectures in medicinal chemistry and materials synthesis.
Methyl 2-(4-iodophenyl)acetate serves as a versatile building block in cross-coupling chemistry, enabling efficient C–C bond formation via palladium-catalyzed reactions. The iodophenyl group exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the ester functionality offers compatibility with subsequent transformations. Its bench-stable nature and straightforward purification make it well-suited for iterative synthesis of complex aryl-containing scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: