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CS-W001157 4
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3,5-Dichlorophenylhydrazine hydrochloride

  • CAS No. 63352-99-8

  • Cat. No. CS-W014964
  • Purity≥97%
  • MDL No.MFCD00012938

*For research and further manufacturing use only, not for direct human use.

3,5-Dichlorophenylhydrazine hydrochloride|CS-W014964

Structure of 63352-99-8

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General Information

  • CAS No. 63352-99-8
  • Cat. No. CS-W014964
  • Purity ≥97%
  • MDL No. MFCD00012938
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇Cl₃N₂
  • Molecular Weight 213.49
  • Synonym(s) 3,5-Dichoropheynylhydrazine hydrochloride
  • SMILES [H+].C1=C(NN)C=C(C=C1Cl)Cl.[Cl-]

Description

3,5-Dichlorophenylhydrazine hydrochloride offers a robust scaffold for heterocyclic synthesis, featuring two electron-withdrawing chlorine substituents that enhance reactivity in cyclization processes. This bench-stable salt delivers high functional group tolerance and facilitates efficient access to triazoles, pyrazoles, and other nitrogen-rich frameworks under standard conditions.

Application

3,5-Dichlorophenylhydrazine hydrochloride serves as a reliable building block for heterocyclic synthesis, particularly in the construction of triazoles and other nitrogen-containing scaffolds. Its stability under standard reaction conditions and compatibility with diverse coupling protocols enable efficient access to functionalized aromatic hydrazones. The dichloro substitution pattern enhances electrophilic reactivity while maintaining bench stability, facilitating purification and integration into multi-step synthetic sequences.

Synthesis

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    • In-stock
      3,5-Dichlorophenylhydrazine hydrochloride|CS-W014964
      63352-99-8

    References

    • Tetrahedron, , vol. 67, # 52 p. 10296 - 10303

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   -0.6045
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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