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Structure of 63452-69-7
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1-Iodo-4-methoxy-2-methylbenzene features a strategically positioned iodine atom flanked by electron-donating methoxy and methyl groups, enhancing reactivity in cross-coupling transformations. This ortho-substituted aryl iodide exhibits excellent stability under standard conditions and facilitates efficient C–C bond formation in palladium-catalyzed reactions.
1-Iodo-4-methoxy-2-methylbenzene serves as a versatile aryl iodide building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The methoxy and methyl groups provide predictable electronic and steric modulation, enhancing reactivity and selectivity. Its bench-stable nature and compatibility with diverse functional groups facilitate reliable synthesis of complex aromatic scaffolds for medicinal chemistry and materials applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: