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Structure of 29632-74-4
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2-Fluoro-4-iodoaniline features a strategically positioned fluorine atom and iodine substituent on the aromatic ring, enabling selective cross-coupling reactions. This electron-deficient aniline derivative offers enhanced stability and reactivity in palladium-catalyzed transformations, facilitating efficient access to complex arylated architectures in medicinal chemistry and materials science.
2-Fluoro-4-iodoaniline serves as a versatile building block for Suzuki-Miyaura and Ullmann coupling reactions, enabling the construction of biaryl scaffolds under mild conditions. The ortho-fluoro substituent enhances regioselectivity in palladium-catalyzed cross-couplings, while the iodide group provides high reactivity in standard transition-metal-mediated transformations. Bench-stable and readily purified by recrystallization, it functions efficiently in the synthesis of fluorinated heterocycles and functionalized arylamines relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: