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CS-W001157 4
Total: USD 88.00

3-(1-Aminoethyl)phenol

  • CAS No. 63720-38-7

  • Cat. No. CS-M0013
  • Purity≥97%
  • MDL No.MFCD09046528

*For research and further manufacturing use only, not for direct human use.

3-(1-Aminoethyl)phenol|CS-M0013

Structure of 63720-38-7

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General Information

  • CAS No. 63720-38-7
  • Cat. No. CS-M0013
  • Purity ≥97%
  • MDL No. MFCD09046528
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) None
  • SMILES NC(C)C1=CC(O)=CC=C1

Description

This 3-(1-aminoethyl)phenol features a phenolic hydroxyl group flanked by an electron-rich aromatic ring and a primary amine-bearing side chain, enabling dual functionalization in synthetic sequences. The pendant amine facilitates conjugation or metal coordination, while the hydroxyl group supports derivatization via etherification or esterification. This bifunctional scaffold integrates readily into bioactive molecule frameworks under standard conditions.

Application

3-(1-Aminoethyl)phenol serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted anilines and bioactive heterocycles. Its ortho-phenolic functionality facilitates direct electrophilic substitution and metal-catalyzed coupling reactions, while the primary amine supports facile derivatization via acylation, alkylation, or imine formation. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for multi-step synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H335
Precautionary Statements : P260-P261-P264-P271-P280-P304+P340-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.4119
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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